First baby born after deceased womb transplant

05 December, 2018, 22:58 | Author: Lillian Steele
  • Doctors hold a baby girl born to a mother who received a uterus from a deceased donor in Brazil. A novel transplantation procedure may help more infertile women become pregnant

The baby girl was born in Sao Paulo, Brazil, late past year following a successful 10 hour uterus transplant to a patient who had been born without a womb.

The mother in the Brazil case was born without a uterus as a result of Mayer-Rokitansky-Kuster-Hauser syndrome. She received the uterus during a 10.5-hour surgery in September 2016 from a 45-year-old donor who had died of a stroke. In this case, a cesarean section was performed for birth at 35 weeks gestation, and along with the delivery of an nearly 6 pound healthy baby girl, the uterus was also removed.

A mother has given birth to a healthy baby girl after surgeons implanted a womb in her body taken from a dead person.

It comes after 10 previously known cases of uterus transplants from deceased donors - in the United States, the Czech Republic and Turkey - failed to produce a live birth.

Until recently, the only options available to women with so-called uterine infertility were adoption or the services of a surrogate mother.

News of the procedure was disclosed in The Lancet medical journal.

Procedures using organs from live donors have been attempted 39 times in the years since, so far resulting in a total of 11 live births. After the transplant, her period returned after 37 days.

Women who would be candidates for a uterus transplant would have absolute uterine infertility, meaning they don't have a uterus or that it is too damaged to support a pregnancy.

Research leader Dr Dani Ejzenberg, of University of Sao Paulo in Brazil, said: "The use of deceased donors could greatly broaden access to this treatment.for women with uterine infertility".

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Five months after the surgery, the medical team observed no signs of rejection, noting that ultrasound scans were normal and the recipient experienced regular menstruation.

"The number of people willing and committed to donate organs upon their own death are far larger than those of live donors, offering a much wider potential donor population", he said in a statement. But they said that relying on deceased donors could expand the options for women who do not have a friend or family member willing to donate or that would be a good match.

The woman became pregnant through in vitro fertilization seven months after the transplant.

Two months later eight fertilised eggs were implanted into the womb.

At age seven months and 12 days - when the manuscript reporting the findings was submitted for publication - the baby was breastfeeding and weighed 7.2kg.

"One will never be able to find whether the dead woman has had any infections in the uterus, nor in the vaginal canals and whether it is treatable or not", Ms Rao told IANS.

"We must congratulate the authors", commented Srdjan Saso, an honourary clinical lecturer in obstetrics and gynaecology at Imperial College London, describing the findings as "extremely exciting". Uterine transplantation began in other countries where there are legal or ethical barriers to surrogacy-getting someone else to carry the pregnancy-O'Neill says.

"This is a great alternative compared to live donor uterus transplants and therefore a really historic achievement", said Dr. Tullius, who is also a professor of surgery at Harvard University.


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