The company said it would acquire Endocyte, headquartered in West Lafayette, Indiana, for $2.1 billion, or $24 per share.
Endocyte uses drug conjugation technology to develop targeted therapies with companion imaging agents for the treatment of cancer.
The purchase of Endocyte will be an all cash transaction and once the deal closes, Endocyte will become part of Novartis, under a newly formed subsidiary. It is expected to be completed in the first half of 2019, subject to approval by Endocyte stockholders, antitrust and regulatory approvals and other customary closing conditions.
Novartis said in September that it will cut 2,550 jobs in Switzerland and Britain over four years, as the it strives to boost profits and focus on new medicines. It is now in a phase 3 registration trial - called VISION - that is due to report results in 2020.
The contrasts of Mexico's southern and northern borders
It was explaining the options to migrants and helping those who chose to apply for refugee status to navigate the lengthy process. And he threatened to send troops to "shut down" the southern USA border if Mexico failed to stop what he called an "onslaught".
Under the agreement, Novartis will acquire all outstanding shares of Endocyte common stock for $US24 apiece -totaling $US2.1 billion - in cash.
"We are also excited about the opportunity to break into the prostate cancer arena with a near-term product that has the potential to make a meaningful impact for patients in great need of more options", Barrett added.
The Endocyte pipeline includes additional investigational RLTs, including Ac-PSMA-617 in preclinical studies for the treatment of mCRPC.
Radiopharmaceuticals such as Lu-PSMA-617 are innovative medicinal formulations containing radioisotopes that are used clinically for both diagnosis and therapy.
Endocyte shares closed on Thursday at $23.40, up 50.39% on the day. Novartis markets the first Food and Drug Administration-approved CAR-T, Kymriah (tisagenlecleucel), which is engineered to target CD19, an antigen expressed on the cells of acute lymphoblastic leukemia and diffuse large B-cell lymphoma, for which it is approved.
According to PEOPLE , the couple held an intimate ceremony in upstate NY , with less than 80 people in attendance. Lots of brides opt for traditional, classic dresses on their big day and Karlie Kloss is no different.
Houston boosted its rotation with Gerrit Cole last winter and its bullpen with Roberto Osuna ahead of the July trade deadline. Martinez opening the scoring with a home run in the third, followed by Rafael Devers three-run homer in the sixth inning.
According to the FT, he will begin work with Facebook over the coming weeks before relocating to Silicon Valley in the new year. Clegg will succeed Elliot Schrage, who announced his departure from Facebook in June. "I am delighted to be joining Facebook".
Meghan's mother, Doria Ragland , is also thrilled and "looks forward to welcoming her first grandchild", the palace added. Plus, find out how Harry opened up about his past mental health struggles in a close-knit gathering with locals.
The snow provides a barrier between the air and the ice, which insulates it from warming temperatures, comparing it to a fur coat. The Ross Ice Shelf in Antarctica it is emitting tones reminiscent of a didgeridoo, or the drone of a horror film soundtrack.
They're also a cheaper alternative to the $7,000 to $10,000 that smugglers, charge for passage to the border, Leutert noted. In recent years, Mexico has deported more Central American immigrants than the United States.
But despite acts of public defiance and rallies, both groups haven't been engaged in any violent activities in Crimea. Soon after the attack, Russian officials said they were investigating the possibility that it was terrorism.
SARKAR Teaser : Vijay’s show all the way
He vows to change the system in a single day, and ends up in a series of slow motion brawls and action sequences. As promised, the makers of the film unveiled the Sarkar teaser at 6 PM today (October 19, 2018).
Saudi explanation for journalist's death is 'credible'
The disappearance of Khashoggi has tarnished Prince Mohammed's reputation and deepened questions about his leadership. The kingdom also said that 18 suspects were in custody and that intelligence officials had been fired.
Duchess of Sussex compares pregnancy to 'jet lag'
A local named Charlotte Connell, who is also expecting, told Sky News she chatted with Meghan about pregnancy . Adding, "She hasn't just got jet lag but she's got a lovely baby on the way as well".
Harry and Meghan’s Australian tour
The Duchess of Sussex's mother Doria Ragland is African-American while her father, Thomas Markle , is caucasian. " Meghan said [yoga] was her "leveller", it's what keeps her grounded, like surfing does for us".
Trump Calls Elizabeth Warren a Total Fraud
For the white-grievance set, it's a powerful piece of rhetoric, created to mock Warren and her fellows who think they know better. In his report, Bustamante said he analysed Warren's sample without knowing the identity of the donor.