At 11:00 am (1600 GMT), the eye of the storm was about 485 miles (785 kms) southeast of Wilmington, North Carolina, moving in a northwest direction at 15 mph (24 kph).
Its maximum sustained winds have dropped slightly to 110 miles per hour.
Large and risky, Hurricane Florence is drawing closer to the coast of the Carolinas, where it threatens to become the most intense storm to strike the region in at least 25 years, since Hugo.
Their entire neighborhood evacuated in Wilmington, North Carolina, David and Janelle Garrigus planned to ride out Florence at their daughter's one-bedroom apartment in Charlotte.
"It's chilling, even from space", said Alexander Gerst, an astronaut with the European Space Agency who now lives on ISS, on Twitter.
Emergency workers monitor hurricane progress at the Emergency operations centre in Wilmington, North Carolina.
In addition to the hurricane-strength winds blowing ashore Friday, Florence has the potential to bring a storm surge upwards of 6 feet in parts of the coastline including up to 13 feet from Cape Fear north to Cape Lookout. "He lives in North Carolina".
Tropical storm Florence lumbered inland on Saturday, knocking down trees, flooding rivers, and dumping sheets of rain in the Carolinas where five people have died.
Images captured with a wide-angle lens on board the Space Station have shown the mind-boggling scale of Hurricane Florence as it nears America's East Coast.
Crews also prepared 16 nuclear reactors in the three-state region for the storm. Governors of those states have already declared states of emergency, as have the governors of Virginia and Maryland.
Industrial waste, including toxic ash from power plants, could also be spread by flooding from the massive storm, which has caused mandatory evacuations of coastal areas in both Carolinas and Virginia, the AP reports.
Florence is the most unsafe of three tropical systems in the Atlantic.
"The time to prepare is nearly over", said North Carolina Governor Roy Cooper at a Wednesday morning news conference.
"Rather than a very narrow and intense band of winds, the winds are slightly weaker - but [they] cover a much larger area", NHC senior hurricane specialist Stacy Stewart said on Wednesday.
The storm's centre is expected to slow when it reaches inland, meaning it could rain for days in places and some areas could see three feet of rain.
To back up that point, Graham cited a sobering statistic: "50 percent of the fatalities in these tropical systems is the storm surge - and that's not just along the coast".
As Florence drew near, President Donald Trump tweeted that Fema and first responders are "supplied and ready", and he disputed the official conclusion that almost 3,000 people died in Puerto Rico, claiming the figure was a Democratic plot to make him look bad.
Baltimore: Flacco and the Ravens offense took almost an entire half of football to get into a groove, and by then it was too late. Pressure had a lot to do with it, but Flacco never looked to be in any rhythm in a stadium where he has historically struggled.
A previous interception of bombers occurring on September 1 involved bombers without any Russian fighter jet escorts, CNN noted . A group of Russian nuclear-capable aircraft ventured near Alaska on september 11 before being intercepted by U.S.
Cooper said 108 shelters are open across the state, with more than 7,000 people already staying at them, as of Thursday afternoon. More than 1.7 million people in the Carolinas and Virginia were warned to evacuate, but it is not clear how many left.
Another annoyance will likely come from the fact that Nintendo won't hold onto your cloud saves if your subscription isn't active. The new version adds gyro controls, HD rumble and single Joy-Con controls for multiplayer battles.
The city of New Bern, with a population of around 30,000, is under a mandatory evacuation, according to The Weather Channel . The center downgraded Florence to a Category 1 hurricane, but warned that it still carried "very unsafe winds".
The attorney general and Department of Homeland Security then have another 45 days to assess whether sanctions should be imposed. First, it requires the Director of National Intelligence to conduct regular assessments of possible election interference.
The monster storm felled trees all around Wilmington, causing many more close calls and damaging homes and cars. "You can never predict what a hurricane is going to do but I'm just not going to run away from this".
In the footage Grande shared of Mac , the rapper appears to be preparing to tell a story before he notices Grande recording him. Miller and Grande dated from August 2016 to May 2018 and remained on good terms until his death , according to PEOPLE .
Apple has just announced the iPhone XS and XS MAX , a new generation of iPhones that brings iPhone photographer to the next level. The new iPhone XS has a 5.8-inch screen size , while iPhone XS Max is 6.5 inch in size , in line with Wall Street expectations.
Dr Adam Marshall, director general of the British Chambers of Commerce, added that key questions remained unanswered. Raab told BBC radio he did not believe May's government would lose a vote in parliament on the deal.
I'm really happy there", he added. "I do not feel judged by a defeat or victory". "I'm at the club that interests me". I recently met his parents and understood a lot about why he is a fantastic guy". "He's an incredible boy".
The changing death toll from Hurricane Maria
Trump has been laser-focused on hurricane response this week, just not this one", says Colbert. He's now falsely claiming that 3,000 people did not die in the wake of the devastating storm.
IPhone XR: Everything you need to know!
The new Apple Watch 4 will come in 40mm and 44mm screen sizes and will be offered in a choice of three aluminium finishes. There's still a notch on top but with a bigger screen, you at least have some more area to left and right of the notch.
Teenager killed as 'gas explosions' set homes ablaze
Authorities said Leonel Rondon, 18, of Lawrence, died after a chimney toppled by an exploding house crashed into his vehicle . To assist with the recovery, the American Red Cross established shelters in Lawrence and Andover that also accommodate pets.