Centuries from Jonny Bairstow (139) and Alex Hales (147), plus a 21-ball half-century from Eoin Morgan helped them eclipse the 444/3 they scored at the same venue against Pakistan two years ago.
England won their 2nd ODI series on the trot against Australia but defending the visitors by a huge 242-run margin after they posted a record total batting first.
Morgan became England's leading run-scorer in his 30-ball 67 runs.
The crushing victory was England's third in the ODI series and means they have an unassailable lead with two games to spare.
Tuesday's defeat was Australia's heaviest defeat at this level, in terms of runs, surpassing a 206-run loss to New Zealand in Adelaide in 1986, reported PTI.
England, then, are three up with two to play and pushing to complete their first ever 5-0 one-day whitewash of the old enemy to follow their 4-1 success in Australia last winter while retaining their status as the No1-ranked side in the world at Durham on Wednesday and Manchester on Sunday.
Eoin Morgan's men were in a similar position during the ODI series in Australia this winter, of course.
England spinners Adil Rashid (four for 47) and Moeen Ali (three for 28), with a mountain of runs behind them, shared seven wickets.
The brutal onslaught which proved to be a worthy entertainer for the fans present at the Trent Bridge was initiated by the England opening pair of Jason Roy and Jonny Bairstow who set the tone for a massive total with a mammoth 159 runs stand for the opening wicket.
Bairstow had two scares, overturning an lbw verdict on 27 sweeping at Ashton Agar and escaping a very hard chance to Marcus Stoinis at deep mid-off three runs later off Andrew Tye, but he powered on to a 69-ball century.
The carnage was still on with Alex Hales joining Bairstow. Mick Lewis conceded 113 runs against South Africa in the 2006 Johannesburg ODI.
"That was extraordinary, some of the best striking I've seen, to be honest, so you've got to take your hat off to the England boys", said Australia captain Tim Paine.
"As good as the wicket was, to score 481, we saw a batting masterclass there from Bairstow, Roy and Hales", the former Australia captain told Sky Sports Cricket.
"The sky's the limit with these guys", Morgan added after England, the 2019 World Cup hosts, cemented their place at the top of the ODI rankings in style.
But after watching Harry Kane lead England to victory in injury time, he had a warning for Martinez: "Watch out". Colombia start the day's action against Japan at midnight (NZT), followed by Poland's clash with Senegal at 3am.
Zara Phillips Tindall and her husband, Mike Tindall , have welcomed their second daughter, Buckingham Palace confirmed on Tuesday. Mike and Zara Tindall both attended Prince Harry and Meghan Markle's wedding on Saturday 19 May, 2018 .
While Germany has won the tournament four times, Mexico had never advanced past the quarterfinals before. I thought we would not have a chance. "Our team might not be playing but we are here for Mexico ".
They also declined to give any detail of the victims although reports said several of them were well known to the police. Police have sealed off a main street running through Sweden's third largest city as officers hunt for the shooter.
The Lakers could include future draft picks as well, but other teams could feasibly put together offers just as good or better. The Kings have the NBA's longest playoff drought at 12 straight seasons and are attempting to become relevant again.
The daughter-in-law of a bobcat trapper, Phillips knew she was dealing with a lethal animal - and needed to act fast. An online fundraising account has been established to help with her medical expenses, which can be found here.
Federer, also marking his return from three months off, is assured of reclaiming the No. 1 ranking from Rafael Nadal on Monday. Federer improved to 21-2 on the season after playing in the 24th grass final of his career.
Nicknamed the Teranga Lions, the team stands at the 28th spot in the Federation Internationale de Football Association rankings. Asked if the problem was the attacking 4-2-3-1 formation he picked, Nawalka said "no, that's now why we lost".
Police are searching for the two armed suspects and have urged anyone who witnessed the shooting to come forward. The rapper, whose real name was Jahseh Dwayne Onfroy, was later pronounced dead, the sheriff's department said.
Dries Mertens' stunning volley finally sprung the Red Devils into action, with Romelu Lukaku then scoring a six-minute brace. Belgium could get away with it here because Michael Murillo didn't punish him as much as other teams would have.
Meanwhile, border patrol agents are heard cracking jokes about the noise, saying, "Well, we have an orchestra here". Republican lawmakers searching for a compromise to stop the practice of separating parents and children at the U.S.
Oppo Find X Joins Full-Screen Club, Brings Pop-Up Camera
We're not sure how sturdy the slide-up mechanism is, but it should be built for major wear and tear, if it is to serve this way. The Find X battery measures in at 3750mAh and it's running Android 8.1 Oreo out of the box under Oppo's proprietary Color OS.
United States plans to withdraw from UN Human Rights Council
State Dept.is making the historic move to protest what it calls is the Council's anti-Israel bias . "USA leadership matters. The move also comes in the days following the United States' president embracing the world's worst murderous dictator.
Early red card dooms Colombia in 2-1 loss to Japan
Colombia began the game without Rodriguez, a Bayern Munich midfielder who was the leading scorer at the 2014 World Cup in Brazil. Colombia will clash with Japan today in the opening Group H fixture at the Mordovia Arena, Saransk.
Brazil lead Switzerland 1-0 at halftime
At the 2010 World Cup, Switzerland managed to beat Spain in its opener, and the Spanish went on to win the tournament. While this Brazil team no longer relies on him, there is still a little bit of Neymar that wishes it did.